A requirement for ankyrin binding to clathrin during coated pit budding.

@article{Michaely1999ARF,
  title={A requirement for ankyrin binding to clathrin during coated pit budding.},
  author={Peter Michaely and Aejaaz Kamal and Richard G. W. Anderson and Vann Bennett},
  journal={The Journal of biological chemistry},
  year={1999},
  volume={274 50},
  pages={35908-13}
}
Recent studies suggest that the mobility of clathrin-coated pits at the cell surface are restricted by an actin cytoskeleton and that there is an obligate reduction in the amount of spectrin on membranes during coated pit budding. The spectrin-actin cytoskeleton associates with membranes primarily through ankyrins, which interact with the cytoplasmic region of numerous integral membrane proteins. We now report that the fourth repeat domain (D4) of ankyrin(R) binds to the N-terminal domain of… CONTINUE READING
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