A requirement for CARMA1 in TCR-induced NF-kappa B activation.

  title={A requirement for CARMA1 in TCR-induced NF-kappa B activation.},
  author={Donghai Wang and Y Nancy You and Sara M. Case and Linda M. McAllister-Lucas and Lin Lin Wang and Peter S Distefano and Gabriel N{\'u}{\~n}ez and John Bertin and Xin Lin},
  journal={Nature immunology},
  volume={3 9},
Stimulation of the T cell receptor (TCR) complex initiates multiple signaling cascades that lead to the activation of several transcription factors, including the NF-kappa B family members. Although various proximal signaling components of the TCR have been intensively studied, the distal components that mediate TCR-induced NF-kappa B activation remain… CONTINUE READING