A requirement for ARF6 during the completion of cytokinesis.

  title={A requirement for ARF6 during the completion of cytokinesis.},
  author={Jill Kuglin Schweitzer and Crislyn D'Souza-Schorey},
  journal={Experimental cell research},
  volume={311 1},
During cancer development, coordinated changes in cell motility and cell cycle progression are required for the gradual transformation of normal cells into cancer cells. Previous studies have shown that ARF6 is a critical regulator of epithelial cell integrity and motility via its role in membrane movement and actin-based cytoskeletal remodeling. Recently, we have found that ARF6 also plays a role during cell division. It localizes to the cleavage furrow and midbody of cells during mitosis, and… CONTINUE READING


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