A report card to grade Helicobacter pylori therapy.

  title={A report card to grade Helicobacter pylori therapy.},
  author={David Y Graham and Hong Lu and Yoshio Yamaoka},
  volume={12 4},
Helicobacter pylori causes a serious bacterial infectious disease, and the expectations of therapy should reflect this fact. Increasing antibiotic resistance, especially to clarithromycin, has significantly undermined the effectiveness of legacy triple therapy consisting of a proton pump inhibitor, clarithromycin, and amoxicillin. Current cure rates are consistently below 80% intention-to-treat, the accepted threshold separating acceptable from unacceptable treatment results. Grading clinical… CONTINUE READING


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