A replicational model for DNA recombination between direct repeats.

@article{Bi1996ARM,
  title={A replicational model for DNA recombination between direct repeats.},
  author={X Bi and Leroy F. Liu},
  journal={Journal of molecular biology},
  year={1996},
  volume={256 5},
  pages={849-58}
}
DNA rearrangement (recombination) mediated by direct repeats is a major cause of genome instability. In Escherichia coli, direct repeats in close proximity can mediate efficient recA-independent intramolecular recombination, which produces multiple products. Using plasmid substrates, three basic forms of products have been revealed: the monomeric deletion product and two dimeric products. The frequency of recombination has been shown to be affected by structural factors such as the length of… CONTINUE READING