A replication study confirmed the EDAR gene to be a major contributor to population differentiation regarding head hair thickness in Asia

@article{Fujimoto2008ARS,
  title={A replication study confirmed the EDAR gene to be a major contributor to population differentiation regarding head hair thickness in Asia},
  author={A. Fujimoto and J. Ohashi and N. Nishida and T. Miyagawa and Y. Morishita and T. Tsunoda and R. Kimura and K. Tokunaga},
  journal={Human Genetics},
  year={2008},
  volume={124},
  pages={179-185}
}
  • A. Fujimoto, J. Ohashi, +5 authors K. Tokunaga
  • Published 2008
  • Biology, Medicine
  • Human Genetics
  • Hair morphology is a highly divergent phenotype among human populations. [...] Key Method In this study, we examined the association of 1540T/C with hair morphology in a Japanese population (Northeast Asian). As observed in our previous study, 1540T/C showed a significant association with hair cross-sectional area (P = 2.7 × 10−6) in Japanese. When all populations (Thai-Mai, Indonesian, and Japanese) were combined, the association of 1540T/C was stronger (P = 3.8 × 10−10) than those of age, sex, and population…Expand Abstract
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    References

    SHOWING 1-10 OF 28 REFERENCES
    A scan for genetic determinants of human hair morphology: EDAR is associated with Asian hair thickness.
    • 186
    • PDF
    Enhanced ectodysplasin‐A receptor (EDAR) signaling alters multiple fiber characteristics to produce the East Asian hair form
    • 90
    • PDF
    A genomewide association study of skin pigmentation in a South Asian population.
    • 258
    A three-single-nucleotide polymorphism haplotype in intron 1 of OCA2 explains most human eye-color variation.
    • 212
    • PDF
    Genetic determinants of hair, eye and skin pigmentation in Europeans
    • 608
    • PDF
    Positive Selection in East Asians for an EDAR Allele that Enhances NF-κB Activation
    • 92
    • Highly Influential
    • PDF
    Genomic regions exhibiting positive selection identified from dense genotype data.
    • 239
    • Highly Influential
    • PDF
    What is normal black African hair? A light and scanning electron-microscopic study.
    • 95