A repetitive, steady mouth opening induced an osteoarthritis-like lesion in the rabbit temporomandibular joint.

@article{Fujisawa2003ARS,
  title={A repetitive, steady mouth opening induced an osteoarthritis-like lesion in the rabbit temporomandibular joint.},
  author={Takuo Fujisawa and Takuo Kuboki and Tadakatsu Kasai and Wataru Sonoyama and Shunji Kojima and Junji Uehara and Chiaki Komori and Hirofumi Yatani and Takako Hattori and Masayuki Takigawa},
  journal={Journal of dental research},
  year={2003},
  volume={82 9},
  pages={731-5}
}
Although excessive mechanical stress is assumed to be one of the factors contributing to pathogenesis of temporomandibular joint (TMJ) osteoarthritis (OA), no pure mechanical-stress-induced OA model has been developed without surgical manipulation or puncture of the joint cavity. The purpose of this study was to establish a genuine mechanical-stress-induced OA model of the rabbit TMJ. In the experimental rabbits, repetitive, forced jaw-opening, 3 hrs/day for 5 days, was applied with the use of… CONTINUE READING
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