A reliable method for evaluating drug compliance in children with cancer

@article{Smith1979ARM,
  title={A reliable method for evaluating drug compliance in children with cancer},
  author={S. Smith and D. Rosen and R. Trueworthy and J. Lowman},
  journal={Cancer},
  year={1979},
  volume={43}
}
Poor drug compliance may cause a decreased survival of children with malignancies. Children who fail to take their medications are not receiving optimum amounts of chemotherapy and suboptimal therapy causes a shortened survival in children with cancer. This is a study of prednisone compliance in 52 children with cancer during three distinct phases of therapy. The patients were either known to be taking prednisone (on‐therapy group), off prednisone (off‐therapy group), or their compliance was… Expand
The effect of compliance with treatment on survival among patients with hematologic malignancies.
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Results suggest that non-compliance is one of the mechanisms which underlies the adverse influence of socioeconomic factors on the outcome of children with acute lymphoblastic leukaemia. Expand
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TLDR
Adolescent age, the higher number of siblings, lack of written instructions, long time spent per visit, and high cost to come for follow-up visits were associated with higher rates of nonadherence, although none reached statistical significance. Expand
with chemotherapy Africa Compliance leukaemia in
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Assessment of drug compliance should be included as an independent variable when evaluating factors affecting response to chemotherapy in communities of diverse ethnic, socio-economic and cultural backgrounds. Expand
Non-compliance with oral chemotherapy in childhood leukaemia
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Adherence to Leukemia Maintenance Therapy: A Comparative Study Among Children, Adolescents, and Adults
TLDR
Outings, the administration of therapy at bedtime, the lack of monitoring, a low socioeconomic status, and the hepatic side effects of the treatment were also associated with nonadherence, which increased with age, but also existed among children. Expand
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