A rehabilitation exercise program induces severe bone mineral deficits in estrogen-deficient rats after extended disuse.

@article{Yarrow2012ARE,
  title={A rehabilitation exercise program induces severe bone mineral deficits in estrogen-deficient rats after extended disuse.},
  author={Joshua F Yarrow and Sean C. McCoy and J. Andries Ferreira and Jennifer E. Pingel and Bryan Conrad and Thomas J. Wronski and Alyssa A Williams and Stephen E. Borst and Marybeth Brown},
  journal={Menopause},
  year={2012},
  volume={19 11},
  pages={1267-76}
}
OBJECTIVE Both estrogen and mechanical loading regulate bone maintenance. However, mechanical overload seems less effective in enhancing bone mineral density (BMD) in estrogen-deficient women. The aim of this study was to determine whether estradiol (E2) influences early-phase bone adaptations to reambulation (REAMB) and/or rehabilitation exercises after… CONTINUE READING