A region from the medium chain adaptor subunit (mu) recognizes leucine- and tyrosine-based sorting signals.

@article{Bremnes1998ARF,
  title={A region from the medium chain adaptor subunit (mu) recognizes leucine- and tyrosine-based sorting signals.},
  author={T. Bremnes and Vigdis Lauvrak and Birgitta Lindqvist and Oddmund Bakke},
  journal={The Journal of biological chemistry},
  year={1998},
  volume={273 15},
  pages={8638-45}
}
Tyrosine-based sorting signals in the cytosolic tails of membrane proteins have been found to bind directly to the medium chain subunit (mu) of the adaptor complexes AP-1 and AP-2. For the leucine-based signals, an interaction with AP-1 and AP-2 has been reported, but no specific interacting subunit has been demonstrated. After searching for molecules interacting with the leucine-based sorting signals within the cytosolic tail of the major histocompatibility complex class II-associated… CONTINUE READING