A regenerative electrochemical biosensor for mercury(II) by using the insertion approach and dual-hairpin-based amplification.

@article{Jia2015ARE,
  title={A regenerative electrochemical biosensor for mercury(II) by using the insertion approach and dual-hairpin-based amplification.},
  author={Jing Jia and Yu Ling and Zhong Feng Gao and Jing Lei Lei and Hong Qun Luo and Nian Bing Li},
  journal={Journal of hazardous materials},
  year={2015},
  volume={295},
  pages={63-9}
}
A simple and effective biosensor for Hg(2+) determination was investigated. The novel biosensor was prepared by the insertion approach that the moiety-labeled DNA inserted into a loosely packed cyclic-dithiothreitol (DTT) monolayer, improving the hybridization efficiency. Electrochemical impedance spectroscopy studies of two biosensors (single-hairpin and dual-hairpin structure DNA modified electrodes) used for Hg(2+) detection indicated that the dual-hairpin modified electrode had a larger… CONTINUE READING

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