A redox active and electrochemiluminescent threading bis-intercalator and its applications in DNA assays.

  title={A redox active and electrochemiluminescent threading bis-intercalator and its applications in DNA assays.},
  author={Hong Xie and Natalia C. Tansil and Zhiqiang Gao},
  journal={Frontiers in bioscience : a journal and virtual library},
A redox active and electrochemiluminescent (ECL) threading bis-intercalator, consisting of two N,N'-bis(3-propyl-imidazole)-1,4,5,8-naphthalene diimides (PIND) linked by a Ru(dmbpy)2(2+) (dmbpy = 4,4'-dimethyl-2,2'-bipyridine) complex (PIND-Ru-PIND), was synthesized for the first time. Its optical, electrochemical, and ECL properties were studied. UV-vis spectrophotometric measurements indicated that the two PIND groups bind to the double-stranded DNA (ds-DNA) in a threading intercalation mode… 

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