A receptor in pituitary and hypothalamus that functions in growth hormone release.

Abstract

Small synthetic molecules termed growth hormone secretagogues (GHSs) act on the pituitary gland and the hypothalamus to stimulate and amplify pulsatile growth hormone (GH) release. A heterotrimeric GTP-binding protein (G protein)-coupled receptor (GPC-R) of the pituitary and arcuate ventro-medial and infundibular hypothalamus of swine and humans was cloned… (More)

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@article{Howard1996ARI, title={A receptor in pituitary and hypothalamus that functions in growth hormone release.}, author={Andrew D. Howard and Scott D. Feighner and Doris F. Cully and Joseph P. Arena and Paul A. Liberator and Charles I. Rosenblum and M Hamelin and Donna L Hreniuk and Oksana C Palyha and Jonathan Anderson and Philip S. Paress and Cristina Diaz and Maeo S Chou and Kang Liu and K K Mckee and S S Pong and L Y Chaung and Alex Elbrecht and Michael P Dashkevicz and Robert P. Heavens and Michael Rigby and Dalip J.S. Sirinathsinghji and Dennis C Dean and David G Melillo and Arthur A. Patchett and Ravi P Nargund and Patrick R. Griffin and Julie A Demartino and Shilpa Gupta and James M. Schaeffer and Roy G. Smith and Lex H.T. Van der Ploeg}, journal={Science}, year={1996}, volume={273 5277}, pages={974-7} }