A recently evolved sublineage of the Mycobacterium tuberculosis Beijing strain family is associated with an increased ability to spread and cause disease.

Abstract

This study aimed to reconstruct the evolutionary history of Beijing strains of Mycobacterium tuberculosis and to test the hypothesis that evolution has influenced the ability of the Beijing strains within the different Beijing sublineages to spread and cause disease. A PCR-based method was used to analyze the genome structure of 40 different loci in 325… (More)

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@article{Hanekom2007ARE, title={A recently evolved sublineage of the Mycobacterium tuberculosis Beijing strain family is associated with an increased ability to spread and cause disease.}, author={Madelene Hanekom and Gian D. van der Spuy and Elizabeth Maria Streicher and S L Ndabambi and Chris McEvoy and M. Kidd and Nulda Beyers and Thomas Calldo Victor and Paul D van Helden and Rob Warren}, journal={Journal of clinical microbiology}, year={2007}, volume={45 5}, pages={1483-90} }