A recent common ancestry for human Y chromosomes

@article{Hammer1995ARC,
  title={A recent common ancestry for human Y chromosomes},
  author={Michael F. Hammer},
  journal={Nature},
  year={1995},
  volume={378},
  pages={376-378}
}
  • M. Hammer
  • Published 1995
  • Biology, Medicine
  • Nature
THE male-specific portion of the Y chromosome is especially useful for studies of human origins. Patterns of nucleotide variation that are neutral with respect to fitness should permit estimates of when and where ancestral Y chromosomes existed1. However, variation on the human Y chromosome has been observed to be greatly reduced relative to the autosomes and the X chromosome2–5. One explanation is that selection for a favourable mutation on the non-recombining portion of the Y chromosome has… Expand
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References

SHOWING 1-10 OF 25 REFERENCES
A recent insertion of an alu element on the Y chromosome is a useful marker for human population studies.
  • M. Hammer
  • Biology, Medicine
  • Molecular biology and evolution
  • 1994
TLDR
Phylogenetic comparisons with other Alu sequences reveal that the YAP element is a member of the polymorphic subfamily-3 (PSF-3), a previously undefined subfamily of Alu elements, which support the hypothesis that recently inserted elements result from multiple source genes. Expand
Absence of polymorphism at the ZFY locus on the human Y chromosome.
TLDR
DNA polymorphism in the Y chromosome, examined at a 729-base pair intron located immediately upstream of the ZFY zinc-finger exon, revealed no sequence variation in a worldwide sample of 38 human males, indicating either a recent selective sweep, recent origin for modern Homo sapiens, recurrent male population bottlenecks, or historically small effective male population sizes. Expand
Allelic genealogy and human evolution.
  • N. Takahata
  • Biology, Medicine
  • Molecular biology and evolution
  • 1993
TLDR
Although the population structure prior to the late Pleistocene is less clear, the nature of Mhc polymorphism suggests that the effective size of populations leading to humans was as large as 10(5), hence, the effective population size of humans might have become somewhat smaller in most of the late pleistocene. Expand
Y chromosomal DNA variation and the peopling of Japan.
TLDR
Four loci mapping to the nonrecombining portion of the Y chromosome were genotyped in Japanese populations from Okinawa, the southernmost island of Japan; Shizuoka and Aomori on the main island of Honshu; and a small sample of Taiwanese, confirming the irregular distribution of this polymorphism in Asia. Expand
Sequence Evolution of Mitochondrial DNA in Humans and Chimpanzees: Control Region and a Protein-Coding Region
TLDR
The results show that the pattern of substitution in the control region has diverged since chimpanzees and humans had a common ancestor, and reinforces estimates based on restriction mapping that the last common ancestor of the humans sampled existed less than 200,000 years ago. Expand
Molecular and population genetic analysis of allelic sequence diversity at the human beta-globin locus.
TLDR
Allelic sequence polymorphism at the beta-globin locus was investigated in a group of 36 Melanesians, suggesting an average age of sequence divergence of approximately 450,000 years, consistent with that expected for a neutrally evolving human nuclear locus. Expand
Low nucleotide diversity in man.
TLDR
The nucleotide diversity in humans is very low, probably due to a relatively small long-term effective population size rather than any severe bottleneck during human evolution. Expand
Recent African origin of modern humans revealed by complete sequences of hominoid mitochondrial DNAs.
TLDR
The shallow ancestry of human mtDNAs, together with the observation that the African sequence is the most diverged among humans, strongly supports the recent African origin of modern humans, Homo sapiens sapiens. Expand
Mitochondrial COII sequences and modern human origins.
TLDR
The mitochondrial DNA sequence data from COII and ND4-5 regions therefore do not support this multiregional hypothesis for the emergence of modern humans and are compatible with a 1-Myr-old human mitochondrial ancestor. Expand
Rapid sequence evolution of the mammalian sex-determining gene SRY
TLDR
The coding sequence of SRY in primates is investigated and it is found that evolution has been rapid in the regions flanking the conserved domain. Expand
...
1
2
3
...