A real-world evaluation of oral vancomycin for severe Clostridium difficile infection: implications for antibiotic stewardship programs.

@article{Le2012ARE,
  title={A real-world evaluation of oral vancomycin for severe Clostridium difficile infection: implications for antibiotic stewardship programs.},
  author={Frank Le and Vaneet Arora and Dhara N. Shah and Miguel Salazar and Hannah R. Palmer and Kevin W Garey},
  journal={Pharmacotherapy},
  year={2012},
  volume={32 2},
  pages={129-34}
}
STUDY OBJECTIVE To assess antibiotic treatment patterns and clinical outcomes of patients with Clostridium difficile infection (CDI) based on underlying severity of CDI disease. DESIGN Retrospective analysis of data from a prospective cohort study. SETTING Large tertiary care university hospital. PATIENTS One hundred forty-four patients (mean ± SD age 63 ± 17 yrs) with CDI who received metronidazole (intravenous or oral) or oral vancomycin as their initial therapy option between 2006 and… CONTINUE READING