A real-time PCR assay for quantification of canine adenoviral vectors.


The pre-existing humoral and cellular immunity found in the great majority of the population raises concerns about the clinical efficacy and safety of vectors derived from ubiquitous human adenovirus serotypes. To alleviate these concerns, canine adenovirus type 2 vectors (CAV-2) were developed. Owing to their extraordinary neuronal tropism and efficient… (More)
DOI: 10.1016/j.jviromet.2009.09.010


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