A re-evaluation of the contributions of Apterous and Notch to the dorsoventral lineage restriction boundary in the Drosophila wing.

@article{Miln2003ARO,
  title={A re-evaluation of the contributions of Apterous and Notch to the dorsoventral lineage restriction boundary in the Drosophila wing.},
  author={Marco Mil{\'a}n and Stephen Michael Cohen},
  journal={Development},
  year={2003},
  volume={130 3},
  pages={553-62}
}
The Drosophila limb primordia are subdivided into compartments: cell populations that do not mix during development. The wing is subdivided into dorsal (D) and ventral (V) compartments by the activity of the selector gene apterous in D cells. Apterous causes segregation of D and V cell populations by at least two distinct mechanisms. The LRR transmembrane proteins Capricious and Tartan are transiently expressed in D cells and contribute to initial segregation of D and V cells. Signaling between… CONTINUE READING

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by decapentaplegic

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  • 1999
Highly Influential
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interactions during DV boundary formation in the Drosophila wing

  • M. Milán, L. Pérez, S. M. Cohen
  • 2002

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