A rational pre-catalyst design for bis-phosphine mono-oxide palladium catalyzed reactions

  title={A rational pre-catalyst design for bis-phosphine mono-oxide palladium catalyzed reactions},
  author={Yining Ji and Hongming Li and Alan M. Hyde and Qinghao Chen and Kevin M. Belyk and Katrina W. Lexa and Jingjun Yin and Edward C. Sherer and R. Thomas Williamson and Andrew P J Brunskill and Sumei Ren and Louis-Charles Campeau and Ian W. Davies and Rebecca T. Ruck},
  journal={Chemical Science},
  pages={2841 - 2851}
Detailed mechanistic studies of a Pd-catalyzed asymmetric C–N coupling led to a rational design of a new series of bis-phosphine mono-oxides ligated Pd(ii) pre-catalysts that allow for reliable and complete catalyst activation. 
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