A rat model of smoke inhalation injury: influence of combustion smoke on gene expression in the brain.

@article{Lee2005ARM,
  title={A rat model of smoke inhalation injury: influence of combustion smoke on gene expression in the brain.},
  author={Heung Man Lee and George H. Greeley and DavidN. Herndon and Monali Sinha and Bruce A. Luxon and Ella W. Englander},
  journal={Toxicology and applied pharmacology},
  year={2005},
  volume={208 3},
  pages={
          255-65
        }
}
Acute smoke inhalation causes death and injury in victims of home and industrial fires as well as victims of combat situations. The lethal factors in combustion smoke inhalation are toxic gases and oxygen deficiency, with carbon monoxide (CO) as a primary cause of death. In survivors, inhalation of smoke can result in severe immediate and delayed neuropathologies. To gain insight into the progression of molecular events contributing to smoke inhalation sequelae in the brain, we developed a… CONTINUE READING
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