A rat model of focal embolic cerebral ischemia

@article{Zhang1997ARM,
  title={A rat model of focal embolic cerebral ischemia},
  author={Rui Lan Zhang and Michael Chopp and Zheng Gang Zhang and Quan Jiang and James R. Ewing},
  journal={Brain Research},
  year={1997},
  volume={766},
  pages={83-92}
}
We developed a new model of embolic cerebral ischemia in the rat which provides a reproducible and predictable infarct volume within the territory supplied by the middle cerebral artery (MCA). The MCA was occluded by an embolus in Wistar rats (n = 71). An additional three non-embolized rats were used as a control. Cerebral blood flow (CBF) was measured by means of laser Doppler flowmetry (LDF) and perfusion weighted imaging (PWI) before and after embolization. The evolution of the lesion was… CONTINUE READING

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