A rapid change in phosphorylation on tyrosine accompanies fertilization of sea urchin eggs.

@article{Ciapa1991ARC,
  title={A rapid change in phosphorylation on tyrosine accompanies fertilization of sea urchin eggs.},
  author={Brigitte Ciapa and David Epel},
  journal={FEBS letters},
  year={1991},
  volume={295 1-3},
  pages={167-70}
}
Alterations in protein phosphorylation, particularly phosphorylation on tyrosine, frequently accompany cell change and are important agents in the cascades initiated by extracellular signals. This paper examines whether the activation of the sea urchin egg at fertilization involves an early and rapid phosphotyrosine response. Using an anti-phosphotyrosine antibody and a rapid sampling technique, we find a very early increase in the phosphorylation on tyrosine of two proteins of approximately 91… CONTINUE READING

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