A rapid bioassay to monitor murine leukemia virus infection in mice using cellular gp 71 binding.

Abstract

A rapid and sensitive bioassay based on the availability of cell surface receptors for the binding of purified envelope glycoprotein, gp71, of Rauscher murine leukemia virus (R-MuLV) was developed to serially monitor viral-induced leukemogenesis in individual BALB/cAnN mice. The specificity of the bioassay was demonstrated by the competition of [125I]gp71… (More)

Topics

  • Presentations referencing similar topics