A rapid, instrument-free, sample-to-result nucleic acid amplification test.
@article{Lafleur2016ARI, title={A rapid, instrument-free, sample-to-result nucleic acid amplification test.}, author={Lisa K Lafleur and Joshua D. Bishop and Erin K. Heiniger and Ryan Gallagher and Max Wheeler and Peter Kauffman and Xiaohong Zhang and Enos C. Kline and Joshua R. Buser and Sujatha Kumar and Samantha A. Byrnes and Nicolaas M. J. Vermeulen and Noah K Scarr and Yevgeniy S. Belousov and Walt Mahoney and Bhushan J. Toley and Paula D Ladd and Barry R. Lutz and Paul Yager}, journal={Lab on a chip}, year={2016}, volume={16 19}, pages={ 3777-87 } }
The prototype demonstrated here is the first fully integrated sample-to-result diagnostic platform for performing nucleic acid amplification tests that requires no permanent instrument or manual sample processing. The multiplexable autonomous disposable nucleic acid amplification test (MAD NAAT) is based on two-dimensional paper networks, which enable sensitive chemical detection normally reserved for laboratories to be carried out anywhere by untrained users. All reagents are stored dry in the…
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