A rapid, highly sensitive and open-access SARS-CoV-2 detection assay for laboratory and home testing

@article{Kellner2020ARH,
  title={A rapid, highly sensitive and open-access SARS-CoV-2 detection assay for laboratory and home testing},
  author={Max J. Kellner and James J. Ross and Jakob Schnabl and M. Dekens and Robert Heinen and Irina Grishkovskaya and Benedikt W. Bauer and Johannes Stadlmann and Luis Men{\'e}ndez-Arias and Andrew D. Straw and Robert Fritsche-Polanz and Marianna Theresia Traugott and Tamara Seitz and Alexander Zoufaly and Manuela F{\"o}dinger and Christoph Wenisch and Johannes Zuber and Andrea Pauli and Julius Brennecke},
  journal={bioRxiv},
  year={2020}
}
Global efforts to combat the Covid-19 pandemic caused by SARS-CoV-2 still heavily rely on RT-qPCR-based diagnostic tests. However, their high cost, moderate throughput and reliance on sophisticated equipment limit widespread implementation. Loop-mediated isothermal amplification after reverse transcription (RT-LAMP) is an alternative detection method that has the potential to overcome these limitations. We present a rapid, robust, sensitive and versatile RT-LAMP based SARS-CoV-2 detection assay… Expand
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