A randomized trial that compared intravaginal misoprostol and dinoprostone vaginal insert in pregnancies at high risk of fetal distress.

@article{Rozenberg2004ART,
  title={A randomized trial that compared intravaginal misoprostol and dinoprostone vaginal insert in pregnancies at high risk of fetal distress.},
  author={P Rozenberg and Sylvie Chevret and Marie-Victoire Senat and Florence Bretelle and Anne Paule Bonnal and Yves Ville},
  journal={American journal of obstetrics and gynecology},
  year={2004},
  volume={191 1},
  pages={247-53}
}
OBJECTIVE The purpose of this study was to compare the safety and efficacy of misoprostol and dinoprostone in pregnancies at high risk of fetal distress. STUDY DESIGN Medical indications for the induction of labor with postdate pregnancy or intrauterine growth restriction were randomized. A sequential design that was based on the triangular test was used. RESULTS At the fourth interim analysis, which included 140 patients, the trial was stopped because no significant difference was found in… CONTINUE READING

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