A randomized trial on effectiveness of artemether-lumefantrine versus artesunate plus amodiaquine for unsupervised treatment of uncomplicated Plasmodium falciparum malaria in Ghanaian children

@article{Kobbe2008ART,
  title={A randomized trial on effectiveness of artemether-lumefantrine versus artesunate plus amodiaquine for unsupervised treatment of uncomplicated Plasmodium falciparum malaria in Ghanaian children},
  author={Robin Kobbe and Philipp Klein and Samuel Adjei and Solomon Amemasor and William Nana Thompson and Hanna Heidemann and Maja Verena Nielsen and Julia Vohwinkel and Benedikt Hogan and Benno Kreuels and Martina B{\"u}hrlen and Wibke Loag and Daniel Ayirebi Ansong and Juergen May},
  journal={Malaria Journal},
  year={2008},
  volume={7},
  pages={261 - 261}
}
Numerous trials have demonstrated high efficacy and safety of artemisinin-based combination therapy (ACT) under supervised treatment. In contrast, effectiveness studies comparing different types of ACT applied unsupervised are scarce. The aim of this study was to compare effectiveness, tolerability and acceptance of artesunate plus amodiaquine (ASAQ) against that of artemether-lumefantrine (AL) in Ghanaian children with uncomplicated Plasmodium falciparum malaria. A randomized open-label trial… CONTINUE READING