A randomized trial of vonapanitase (PATENCY‐1) to promote radiocephalic fistula patency and use for hemodialysis

@article{Bleyer2019ART,
  title={A randomized trial of vonapanitase (PATENCY‐1) to promote radiocephalic fistula patency and use for hemodialysis},
  author={A. Bleyer and Vincent A. Scavo and S. Wilson and B. Browne and B. Ferris and K. Ozaki and T. Lee and E. Peden and B. Dixon and R. Mishler and T. O’Connor and K. Kidd and S. Burke},
  journal={Journal of Vascular Surgery},
  year={2019},
  volume={69},
  pages={507–515}
}
  • A. Bleyer, Vincent A. Scavo, +10 authors S. Burke
  • Published 2019
  • Medicine
  • Journal of Vascular Surgery
  • Objective Arteriovenous fistulas created in patients with chronic kidney disease often lose patency and fail to become usable. This prospective trial evaluated the efficacy of vonapanitase, a recombinant human elastase, in promoting radiocephalic fistula patency and use for hemodialysis. Methods PATENCY‐1 was a double‐blind, placebo‐controlled trial that enrolled 349 patients on or approaching hemodialysis and being evaluated for radiocephalic arteriovenous fistula creation. Of these, 313 were… CONTINUE READING
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