A randomized trial of nonoperative treatment for perforated peptic ulcer.

@article{Crofts1989ART,
  title={A randomized trial of nonoperative treatment for perforated peptic ulcer.},
  author={T J Crofts and Kwang Gil Park and Robert J. C. Steele and Sydney S.C. Chung and Alexander K. Li},
  journal={The New England journal of medicine},
  year={1989},
  volume={320 15},
  pages={
          970-3
        }
}
To determine whether surgery could be avoided in some patients with perforated peptic ulcer, we conducted a prospective randomized trial comparing the outcome of nonoperative treatment with that of emergency surgery in patients with a clinical diagnosis of perforated peptic ulcer. Of the 83 patients entered in the study over a 13-month period, 40 were randomly assigned to conservative treatment, which consisted of resuscitation with intravenous fluids, institution of nasogastric suction, and… CONTINUE READING

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