A randomized trial of ceftriaxone versus oral penicillin for the treatment of early european lyme borreliosis

@article{Weber1990ART,
  title={A randomized trial of ceftriaxone versus oral penicillin for the treatment of early european lyme borreliosis},
  author={Dr. med. Karl-Heinz Weber and Dr. rer. nat. Vera Preac-Mursic and Dr. med. Bettina Wilske and Prof. Dr. med. R. Thurmayr and Dr. med. U. Neubert and Prof. Dr. med. C. Scherwitz},
  journal={Infection},
  year={1990},
  volume={18},
  pages={91-96}
}
In a prospective randomized multicenter trial for the therapy of erythema migrans, 40 patients received ceftriaxone 1 g daily for 5 days and 33 patients obtained phenoxymethylpenicillin, 1 million units 3 times daily, for 12 days. Follow-up was for a mean of 10±5 months. Eight oral penicillin recipients (24%) and six ceftriaxone recipients (15%) developed minor consecutive manifestations. Two ceftriaxone and one penicillin recipient(s) still had elevated IgG antibody titers 10 to 20 months… CONTINUE READING
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