A randomized trial of botulinum toxin A for treatment of drooling

@article{Lipp2003ART,
  title={A randomized trial of botulinum toxin A for treatment of drooling},
  author={Alexandra Lipp and Thomas Trottenberg and Tanja Schink and Andreas Kupsch and G. Arnold},
  journal={Neurology},
  year={2003},
  volume={61},
  pages={1279 - 1281}
}
The authors compared the efficacy of three different doses (18.75, 37.5, and 75 MU per parotid gland) of botulinum toxin A (BTX-A; Dysport, Ipsen Pharma, Germany) injections vs vehicle in patients with sialorrhea (n = 32) using a single-center, prospective, double-blind, placebo-controlled dose-finding study. The primary endpoint was achieved with 75 MU BTX-A without treatment-related adverse events, suggesting BTX-A is a safe and effective treatment for patients with sialorrhea. 
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