A randomized trial of beta carotene supplementation and cognitive function in men: the Physicians' Health Study II.

@article{Grodstein2007ART,
  title={A randomized trial of beta carotene supplementation and cognitive function in men: the Physicians' Health Study II.},
  author={Francine Grodstein and Jae H Kang and Robert J Glynn and Nancy R. Cook and J. Michael Gaziano},
  journal={Archives of internal medicine},
  year={2007},
  volume={167 20},
  pages={
          2184-90
        }
}
BACKGROUND Oxidative stress contributes to brain aging. Antioxidant treatment, especially over the long term, might confer cognitive benefits. METHODS We added cognitive testing to the Physicians' Health Study II (PHSII), a randomized trial of beta carotene and other vitamin supplements for chronic disease prevention. The PHSII is a continuation of the Physicians' Health Study (PHS), which had randomized male participants to low-dose aspirin and beta carotene. Participants include those… CONTINUE READING

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