A randomized trial of aspirin on the risk of embolic events in patients with infective endocarditis.

@article{Chan2003ART,
  title={A randomized trial of aspirin on the risk of embolic events in patients with infective endocarditis.},
  author={Kwan Leung Chan and Jean Gaston Dumesnil and Bibiana Cujec and Anthony J Sanfilippo and John Jue and Michele A Turek and Trevor I Robinson and David Moher},
  journal={Journal of the American College of Cardiology},
  year={2003},
  volume={42 5},
  pages={775-80}
}
OBJECTIVES This study examined the effect of aspirin on the risk of embolic events in infective endocarditis (IE). BACKGROUND Embolism is a major complication of IE, and studies in animal models have shown that platelet inhibition with aspirin can lead to more rapid vegetation resolution and a lower rate of embolic events. METHODS We conducted a randomized, double-blinded, placebo-controlled trial of aspirin treatment (325 mg/day) for four weeks in patients with IE to test the hypothesis… CONTINUE READING

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