A randomized trial comparing the impact of a nonionic (Iomeprol) versus an ionic (Ioxaglate) low osmolar contrast medium on abrupt vessel closure and ischemic complications after coronary angioplasty.

@article{Schraeder1999ART,
  title={A randomized trial comparing the impact of a nonionic (Iomeprol) versus an ionic (Ioxaglate) low osmolar contrast medium on abrupt vessel closure and ischemic complications after coronary angioplasty.},
  author={Rainer Schraeder and Iwan J. P. de Esch and R Ensslen and W. Andreas Fach and Harold Merle and Detlef Scherer and Horst Sievert and H. F. Spies and Harald Zeplin},
  journal={Journal of the American College of Cardiology},
  year={1999},
  volume={33 2},
  pages={395-402}
}
OBJECTIVES To assess the effect of nonionic versus ionic contrast media on abrupt vessel closure and major ischemic complications after coronary angioplasty. BACKGROUND There is a continuous debate about the "thrombogenic potential" of nonionic contrast media. The results of both in vitro and in vivo investigations are incongruent. METHODS We prospectively evaluated the outcomes of 2,000 patients undergoing percutaneous transluminal coronary angioplasty (PTCA). According to a randomized… CONTINUE READING
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