A randomized trial comparing radical prostatectomy with watchful waiting in early prostate cancer.

@article{Holmberg2002ART,
  title={A randomized trial comparing radical prostatectomy with watchful waiting in early prostate cancer.},
  author={Lars H Holmberg and Anna Bill-Axelson and Fred Helgesen and Jaakko Salo and Per Folmerz and Michael H{\"a}ggman and Swen-Olof Andersson and Anders Sp{\aa}ngberg and Christer Busch and S Nordling and Juni Palmgren and Hans-Olov Adami and J Johansson and Bo Johan Norl{\'e}n},
  journal={The New England journal of medicine},
  year={2002},
  volume={347 11},
  pages={
          781-9
        }
}
  • Lars H Holmberg, Anna Bill-Axelson, +11 authors Bo Johan Norlén
  • Published in
    The New England journal of…
    2002
  • Medicine
  • BACKGROUND Radical prostatectomy is widely used in the treatment of early prostate cancer. The possible survival benefit of this treatment, however, is unclear. We conducted a randomized trial to address this question. METHODS From October 1989 through February 1999, 695 men with newly diagnosed prostate cancer in International Union against Cancer clinical stage T1b, T1c, or T2 were randomly assigned to watchful waiting or radical prostatectomy. We achieved complete follow-up through the… CONTINUE READING

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