A randomized trial comparing primary angioplasty with a strategy of short-acting thrombolysis and immediate planned rescue angioplasty in acute myocardial infarction: the PACT trial. PACT investigators. Plasminogen-activator Angioplasty Compatibility Trial.

@article{Ross1999ART,
  title={A randomized trial comparing primary angioplasty with a strategy of short-acting thrombolysis and immediate planned rescue angioplasty in acute myocardial infarction: the PACT trial. PACT investigators. Plasminogen-activator Angioplasty Compatibility Trial.},
  author={A. H. McL Ross and Karin S. Coyne and Jonathan S. Reiner and Samuel W. Greenhouse and Christian Fink and Aline Frey and Eduardo Moreyra and Mouhieddin Traboulsi and Normand Racine and Arthur L. Riba and Meredith Thompson and Steve Rohrbeck and Conor F. Lundergan},
  journal={Journal of the American College of Cardiology},
  year={1999},
  volume={34 7},
  pages={1954-62}
}
OBJECTIVES The study evaluated the efficacy and safety of a short-acting reduced-dose fibrinolytic regimen to promote early infarct-related artery (IRA) patency during the inherent delay experienced by infarct patients referred for angioplasty as the principal recanalization modality. BACKGROUND Previous approaches using long-acting, full-dose thrombolytic infusions rarely showed benefit, but they did increase adverse event rates. METHODS Following aspirin and heparin, 606 patients were… CONTINUE READING

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