A randomized trial comparing lung-volume-reduction surgery with medical therapy for severe emphysema.

@article{Fishman2003ART,
  title={A randomized trial comparing lung-volume-reduction surgery with medical therapy for severe emphysema.},
  author={Alfred P. Fishman and Fernando Mart{\'i}nez and Keith S. Naunheim and Steven Piantadosi and Robert Wise and Andrew Ries and Gail G Weinmann and Douglas E. Wood},
  journal={The New England journal of medicine},
  year={2003},
  volume={348 21},
  pages={2059-73}
}
BACKGROUND Lung-volume-reduction surgery has been proposed as a palliative treatment for severe emphysema. Effects on mortality, the magnitude and durability of benefits, and criteria for the selection of patients have not been established. METHODS A total of 1218 patients with severe emphysema underwent pulmonary rehabilitation and were randomly assigned to undergo lung-volume-reduction surgery or to receive continued medical treatment. RESULTS Overall mortality was 0.11 death per person… CONTINUE READING
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