A randomized trial assessing the effectiveness of different concentrations of isotretinoin in the management of lichen planus.

@article{Scardina2006ART,
  title={A randomized trial assessing the effectiveness of different concentrations of isotretinoin in the management of lichen planus.},
  author={Giuseppe Alessandro Scardina and Pietro Messina and Francesco Carini and Emiliano Antonio Maresi},
  journal={International journal of oral and maxillofacial surgery},
  year={2006},
  volume={35 1},
  pages={67-71}
}
The aim of our 10-year study was to test the effectiveness of topical therapy based on 0.18% isotretinoin, comparing it with that most frequently used, i.e. at 0.05% concentration. Seventy patients with an established diagnosis of oral lichen planus were involved in the study. The patients were randomly divided into two groups, and the drug was administered topically at 0.05% and 0.18% concentrations. The drug at the higher concentration, according to the same protocol, was administered to the… CONTINUE READING

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