A randomized study of chemotherapy, radiation therapy, and surgery versus surgery for localized squamous cell carcinoma of the esophagus.

@article{Prise1994ARS,
  title={A randomized study of chemotherapy, radiation therapy, and surgery versus surgery for localized squamous cell carcinoma of the esophagus.},
  author={E A Le Prise and Pierre Luc Etienne and Brigitte Meunier and Guy J Maddern and Mohamed Ben Hassel and Daniel G{\'e}douin and Du Le Thi Huong Boutin and Jean Pierre Campion and Bernard Launois},
  journal={Cancer},
  year={1994},
  volume={73 7},
  pages={1779-84}
}
BACKGROUND Despite well-established surgical approaches, the prognosis for patients with squamous cell carcinoma of the esophagus remains dismal. To assess the benefit of adjuvant chemotherapy and radiation therapy (CRT), a randomized trial with and without sequential preoperative CRT was undertaken; CRT combined 20 Gy and two courses of 5-FU and cisplatin. METHODS Patients were included on the basis of the following criteria: squamous cell carcinoma of the esophagus, younger than 70 years of… CONTINUE READING
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