A randomized study comparing fluconazole with amphotericin B/5-flucytosine for the treatment of systemic Candida infections in intensive care patients.

@article{Abelehorn1996ARS,
  title={A randomized study comparing fluconazole with amphotericin B/5-flucytosine for the treatment of systemic Candida infections in intensive care patients.},
  author={Marianne Abele-horn and Alex Kopp and Ulrich Sternberg and A Ohly and A Dauber and W. Russwurm and W B{\"u}chinger and O Nagengast and Prof. Dr. med. P. Emmerling},
  journal={Infection},
  year={1996},
  volume={24 6},
  pages={426-32}
}
In this prospective, randomized study fluconazole and amphotericin B/5-flucytosine were compared in the treatment of systemic candidiasis. Seventy-two non-neutropenic intensive care patients with systemic Candida infections were enrolled. Thirty-six patients were randomly assigned to receive fluconazole (400 mg on the first day then 200 mg) and 36 were randomized to amphotericin B/5-flucytosine (1.0-1.5 mg/kg body weight every other day and 3 x 2.5 g flucytosine/day) for 14 days following the… CONTINUE READING

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