A randomized placebo-controlled trial of oxybutynin for the initial treatment of palmar and axillary hyperhidrosis.

@article{Wolosker2012ARP,
  title={A randomized placebo-controlled trial of oxybutynin for the initial treatment of palmar and axillary hyperhidrosis.},
  author={Nelson Wolosker and Jos{\'e} Ribas Milanez de Campos and Paulo Kauffman and Pedro Puech-Le{\~a}o},
  journal={Journal of vascular surgery},
  year={2012},
  volume={55 6},
  pages={1696-700}
}
INTRODUCTION Video-assisted thoracic sympathectomy provides excellent resolution of palmar and axillary hyperhidrosis but is associated with compensatory hyperhidrosis. Low doses of oxybutynin, an anticholinergic medication that competitively antagonizes the muscarinic acetylcholine receptor, can be used to treat palmar hyperhidrosis with fewer side effects. OBJECTIVE This study evaluated the effectiveness and patient satisfaction of oral oxybutynin at low doses (5 mg twice daily) compared… CONTINUE READING