A randomized placebo-controlled trial of duloxetine in patients with major depressive disorder and associated painful physical symptoms.

@article{Gaynor2011ARP,
  title={A randomized placebo-controlled trial of duloxetine in patients with major depressive disorder and associated painful physical symptoms.},
  author={Paula J Gaynor and Murali Gopal and Wei Zheng and J. Mart{\'i}n Mart{\'i}nez and Michael J Robinson and Lauren B. Marangell},
  journal={Current medical research and opinion},
  year={2011},
  volume={27 10},
  pages={1849-58}
}
OBJECTIVE Painful physical symptoms are common in patients with major depressive disorder (MDD) and may predict poorer treatment outcomes. Duloxetine has demonstrated efficacy in treating both MDD and certain other painful conditions. This randomized, double-blind clinical trial assessed the effects of duloxetine in patients with both MDD and MDD-associated physical pain. METHODS Participants were outpatient adults with current MDD (DSM-IV-TR criteria; Montgomery-Åsberg Depression Rating… CONTINUE READING
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