A randomized placebo-controlled study of intravenous montelukast for the treatment of acute asthma.

@article{Camargo2010ARP,
  title={A randomized placebo-controlled study of intravenous montelukast for the treatment of acute asthma.},
  author={Carlos Arturo Camargo and Deborah M Gurner and Howard A. Smithline and Rocio Chapela and Leonardo M Fabbri and Stuart Green and M Malice and Catherine Legrand and S. Balachandra Dass and Barbara A Knorr and Theodore F. Reiss},
  journal={The Journal of allergy and clinical immunology},
  year={2010},
  volume={125 2},
  pages={374-80}
}
BACKGROUND Current treatments for acute asthma provide inadequate benefit for some patients. Intravenous montelukast may complement existent therapies. OBJECTIVE To evaluate efficacy of intravenous montelukast as adjunctive therapy for acute asthma. METHODS A total of 583 adults with acute asthma were treated with standard care during a < or = 60-minute screening period. Patients with FEV(1) < or =50% predicted were randomly allocated to intravenous montelukast 7 mg (n = 291) or placebo (n… CONTINUE READING

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