A randomized pilot trial of oral branched-chain amino acids in early cirrhosis: validation using prognostic markers for pre-liver transplant status.

@article{Kawamura2009ARP,
  title={A randomized pilot trial of oral branched-chain amino acids in early cirrhosis: validation using prognostic markers for pre-liver transplant status.},
  author={Etsushi Kawamura and Daiki Habu and Hiroyasu Morikawa and Masaru Enomoto and Joji Kawabe and A Tamori and Hiroki Sakaguchi and Shigeru Saeki and Norifumi Kawada and Susumu Shiomi},
  journal={Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society},
  year={2009},
  volume={15 7},
  pages={790-7}
}
Because of the chronic shortage of liver donors, hepatologists are required to prolong the liver transplant waiting period by preserving the hepatic reserve of scheduled recipients. This study examined the effectiveness of oral branched-chain amino acids (BCAAs), using outcome markers indicating pretransplant hepatic reserve. Fifty-six consecutive eligible patients with Child class A cirrhosis without major complications were randomly assigned to receive oral BCAA granules (12.45 g/day) for… CONTINUE READING