A randomized phase II study of vinorelbine plus gemcitabine with/without cisplatin against inoperable non-small-cell lung cancer previously untreated.

@article{Chen2005ARP,
  title={A randomized phase II study of vinorelbine plus gemcitabine with/without cisplatin against inoperable non-small-cell lung cancer previously untreated.},
  author={Yuh-Min Chen and R. I. Perng and Jing Ping Shih and Chun-Ming Tsai and Jacqueline Whang-Peng},
  journal={Lung cancer},
  year={2005},
  volume={47 3},
  pages={
          373-80
        }
}
Phase II studies have suggested that vinorelbine (V) plus gemcitabine (G) treatment has a similar response rate and better toxicity profile than cisplatin-based combination chemotherapy in non-small-cell lung cancer (NSCLC). Our aim was to evaluate whether or not the addition of cisplatin (P) to a VG regimen increases the efficacy or toxicities in chemo-naive inoperable NSCLC patients. From April 2002 to October 2003, 86 patients were enrolled. The treatment dose was V 20 mg/m2 plus G 800 mg/m2… CONTINUE READING
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