A randomized open study to assess the efficacy and tolerability of dihydroartemisinin-piperaquine for the treatment of uncomplicated falciparum malaria in Cambodia.

@article{Janssens2007ARO,
  title={A randomized open study to assess the efficacy and tolerability of dihydroartemisinin-piperaquine for the treatment of uncomplicated falciparum malaria in Cambodia.},
  author={Bart Janssens and Michel van Herp and Liesbet Goubert and Shi Hua Chan and Sokhan Uong and Shengxiong Nong and Doung 7 Socheat and Alan Brockman and Elizabeth A Ashley and Wim J M van Damme},
  journal={Tropical medicine & international health : TM & IH},
  year={2007},
  volume={12 2},
  pages={251-9}
}
OBJECTIVES To compare the efficacy and tolerability of dihydroartemisinin-piperaquine (DHA-PQP) with that of a 3-day regimen of mefloquine and artesunate (MAS3) for the treatment of uncomplicated falciparum malaria in Cambodia. METHOD Randomized open-label non-inferiority study over 64 days. RESULTS Four hundred and sixty-four patients were included in the study. The polymerase chain reaction genotyping-adjusted cure rates on day 63 were 97.5% (95% confidence interval, CI, 93.8-99.3) for… CONTINUE READING
28 Citations
16 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 28 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 16 references

DHA–PQP vs. MAS3 against malaria in Cambodia a 2007

  • B. Janssens
  • 2007

mefloquine in falciparum malaria: an open-label randomised comparison

  • TH Tran, C Dolecek, PM Phan
  • 2006

Similar Papers

Loading similar papers…