A randomized controlled trial of the effects of a prudent diet on cardiovascular risk factors , gene expression , and DNA methylation-the Diet and Genetic Intervention ( DIGEST ) Pilot study

@inproceedings{Zulyniak2016ARC,
  title={A randomized controlled trial of the effects of a prudent diet on cardiovascular risk factors , gene expression , and DNA methylation-the Diet and Genetic Intervention ( DIGEST ) Pilot study},
  author={Michael A Zulyniak and Russell J. de Souza and Andrew Mente and Sujane Kandasamy and Monisha Nundy and Dipika Desai and Kripa Raman and Ranya Hasso and Guillaume Par{\'e} and Joseph Beyene and Sonia Savitri Anand},
  year={2016}
}
Background: Risk of cardiovascular disease (CVD) can be increased by single-nucleotide polymorphisms (SNPs) in the 9p21 region of the genome. However, observational studies have shown that the deleterious effect of 9p21 SNPs on CVD might be offset by consuming a diet rich in fresh fruits and vegetables. This association may be driven by diet-influenced… CONTINUE READING