A randomized controlled open comparative trial of varenicline vs nicotine patch in adult smokers: efficacy, safety and withdrawal symptoms (the VN-SEESAW study).

@article{Tsukahara2010ARC,
  title={A randomized controlled open comparative trial of varenicline vs nicotine patch in adult smokers: efficacy, safety and withdrawal symptoms (the VN-SEESAW study).},
  author={Hitomi Tsukahara and Keita Noda and Keijiro Saku},
  journal={Circulation journal : official journal of the Japanese Circulation Society},
  year={2010},
  volume={74 4},
  pages={771-8}
}
BACKGROUND It has been suggested that anti-smoking therapy gives encouraging results, but this has not been verified by well-randomized study protocols. The present study was a randomized controlled trial of varenicline vs nicotine patch in adult smokers for comparison of efficacy, safety and withdrawal symptoms. METHODS AND RESULTS The 32 adult smokers were randomly divided into a varenicline group (VG, n=16) and a nicotine patch group (NG, n=16). The primary endpoints were the 12- and 24… CONTINUE READING

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The MPOWER package

  • World Health Organization. Report on the Global Tobacco Epidemic, 2008
  • http://www.who.int/tobacco/ mpower/en/
  • 2008

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