A randomized , double-blind , futility clinical trial of creatine and minocycline in early Parkinson disease

@inproceedings{2006AR,
  title={A randomized , double-blind , futility clinical trial of creatine and minocycline in early Parkinson disease},
  author={},
  year={2006}
}
  • Published 2006
Background: Creatine and minocycline were prioritized for testing in Phase II clinical trials based on a systematic evaluation of potentially disease modifying compounds for Parkinson disease (PD). Objective: To test whether creatine and minocycline alter the course of early PD relative to a predetermined futility threshold for progression of PD in a randomized, double-blind, Phase II futility clinical trial. Agents that do not perform better than the futility threshold are rejected as futile… CONTINUE READING