A randomized, double masked, controlled trial of botulinum toxin type A in essential hand tremor.

@article{Brin2001ARD,
  title={A randomized, double masked, controlled trial of botulinum toxin type A in essential hand tremor.},
  author={Mitchell F. Brin and Kelly E. Lyons and John T Doucette and Charles H Adler and John N. Caviness and Cynthia L. Comella and Richard M. Dubinsky and Joseph H Friedman and Bala V. Manyam and Joseph Y. Matsumoto and Seth L. Pullman and Ali H. Rajput and Kapil D. Sethi and Caroline Tanner and William C. Koller},
  journal={Neurology},
  year={2001},
  volume={56 11},
  pages={1523-8}
}
OBJECTIVE To evaluate the safety and efficacy of botulinum toxin type A injection in essential tremor of the hand. BACKGROUND Botulinum toxin type A is an effective treatment for dystonia, spasticity, and other movement disorders and has been found to be useful in open-label studies and one double-masked study of essential hand tremor. METHODS One hundred thirty-three patients with essential tremor were randomized to low-dose (50 U) or high-dose (100 U) botulinum toxin type A (Botox) or… CONTINUE READING